Laboratory for Development and Evolution

Department of Zoology

Alan Marron

Alan MarronBBSRC PhD Student

Tel: + 44 (0) 1223 336653 or 31772
Fax: +44 (0) 1223 337766

am543@cam.ac.uk

Interests and research

My PhD research concerns the evolution of silica biomineralization in the eukaryotes. Biomineralization is of great importance from a physiological, biochemical, palaeontological and geochemical point of view. Within the eukaryotes all of the supergroups (except the Excavata) contain silica-forming taxa, however little is known about the homology or convergent evolution of silica biomineralization within or between groups. Is silica formed by a conserved ancestral mechanism, a similar mechanism that has evolved multiple times convergently or has there been many different evolutions of many different mechanisms?

As part of my work I am studying silica formation in choanoflagellates. Choanoflagellates are protists that are the closest unicellular relatives of the Metazoa. One group of choanoflagellates, the Acanthoecids, produce a lorica (basket-like structure) made of silica. I am studying the molecular biology of lorica formation, using bioinformatic analysis of EST and genomic data.

This project is jointly supervised by Michael Akam, Giselle Walker, and Mark Field

Diaphanoeca grandis (x100 magnification bright field)

Diaphanoeca grandis with live cell on left and empty siliceous lorica on right

Choanoflagellate wikipedia