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Current Vacancies

Postdoctoral Research Associate: Evolutionary Genomics (Fixed Term)

From Jobs at the University of Cambridge. Published on Sep 14, 2017.

A post-doctoral research associate position in Department of Zoology, located in Central Cambridge on Downing Street, is available from 1 November 2017 for 18 months, in the first instance, to work with Professor Chris Jiggins on the evolutionary genomics of adaptation and speciation in Heliconius butterflies. The PDRA will use large resequence data sets and high quality reference genomes to study adaptation and speciation in the genus.

Possible projects include: 1) analysis of species boundaries and the influence of recombination rate on patterns of admixture across the Heliconius genome 2) analysis of recombination rate evolution more broadly across the genus and the influence of chromosomal fusions on both recombination rate and population level variation and 3) modelling of selective sweeps at mimicry loci to understand the history of introgression and selection on wing pattern in the context of multiple adaptive introgressions. There is considerable scope for the focus of the biological analyses to reflect the interests of the candidate.

The research will primarily involve bioinformatic analysis of existing genomic sequence datasets. The successful applicant must have a Ph.D. in evolutionary biology, bioinformatics or a related field, with a strong interest in population genomics. In addition, candidates should have experience with the manipulation and analysis of Illumina data and working knowledge of a programing language such as Python or Perl.

Candidates should have a good collaborative spirit, as the work will involve close collaboration with researchers in Cambridge and Panama as well as coordination with many different labs working on Heliconius biology, genome assembly and genome databases.

Duties will include:

  • Designing and carrying out genomics experiments to investigate the origins of mimicry patterns and species diversity in Heliconius;

  • Analyse large resequence data sets in the context of recombination rate variation across the genome;

  • Analysing and writing up the results.

Enthusiasm, determination and the capacity to work independently are also essential.

There will be opportunities for the successful applicant to apply for fellowship funding to continue this work independently in Cambridge.

Fixed-term: The funds for this post are available for 18 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PF13317 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Postdoctoral Research Associate: Genetic basis for cyanogen chemistry in butterflies (Fixed Term)

From Jobs at the University of Cambridge. Published on Sep 14, 2017.

A post-doctoral research associate position in Department of Zoology, located in Central Cambridge on Downing Street, is available from 1 November 2017 for 18 months, in the first instance, to work with Professor Chris Jiggins on the genetic basis for variation in chemical defences among Heliconius butterflies. The project will involve genetic analysis of chemical defence variability among Heliconius butterflies and in particular between H. melpomene and H. cydno, and CRISPR experiments to study the function of genes that are responsible for synthesising cyanogens. There is considerable scope for the focus of the biological analyses to reflect the interests of the candidate.

The successful applicant must have a Ph.D in evolutionary biology, chemical ecology or a related field, with a strong interest in speciation. Candidates should have experience with Gas Chromatography and chemical analysis of butterfly defensive toxins, as well as an understanding of the genetic basis for chemical defence in Heliconius. Candidates should have a good collaborative spirit, as the work will involve close collaboration with researchers in Cambridge and Panama as well as coordination with different labs working on Heliconius biology. Enthusiasm, determination and the capacity to work independently are also essential.

Duties will include:

  • Gas chromatography analysis of specimens collected in the wild;

  • CRISPR experiments to study the effects of candidate genes on chemical defence;

  • Designing and carrying out genetic experiments to investigate the genetic basis for chemical defence in Heliconius;

  • Analysing and writing up the results.

There will be opportunities for the successful applicant to apply for fellowship funding to continue this work independently in Cambridge.

Fixed-term: The funds for this post are available for 18 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PF13313 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Postdoctoral Research Associate: Wing colour pattern genetics (Fixed term)

From Jobs at the University of Cambridge. Published on Sep 14, 2017.

A post-doctoral research associate position in Department of Zoology, located in Central Cambridge on Downing Street, is available from 1 November 2017 for 18 months, in the first instance, to work with Professor Chris Jiggins on the genetic basis of adaptation and speciation in Heliconius butterflies. The PDRA will use CRISPR technology to study the genetic basis of wing patterns in Heliconius. We have used large scale sequencing data to identify narrow regions associated with specific wing pattern elements and these permit detailed experiments to investigate their function.

We are interested in the cortex locus which controls yellow wing patterns between species and populations of Heliconius. Potential experiments include targeted coding sequence knockouts, focusing on the cortex gene; regulatory locus deletions to investigate the effect of candidate regulatory sequence; gene-tagging using knock-ins to investigate patterns of gene expression and function. There is scope for the focus of the biological analyses to reflect the interests of the candidate.

It is likely that the post will involve periods of fieldwork in South America (Colombia, Panama or Ecuador). It is also possible that CRISPR injection experiments could be carried out with collaborators in these countries.

Essential criteria:

  • PhD in an appropriate subject (e.g. evo-devo or evolutionary genetics);

  • Experience with evolutionary genetics research;

  • Ambition and drive, strong work ethic and good interpersonal skills and an exceptional publication record;

  • Enthusiasm to interact with colleagues;

  • Ability to organise time and work effectively, independently and responsibly in a research team setting.

The successful applicant should have a strong interest in the genetic basis for adaptation.

Duties will include:

  • Designing and carrying out genetic manipulation experiments to investigate the origins of mimicry patterns and species diversity in Heliconius;

  • Designing CRISPR experiments for targeted analysis of genetic differences in wing pattern;

  • Managing butterfly care and maintenance of stocks;

  • Analysing and writing up the results.

Candidates should have a good collaborative spirit, as the work will involve close collaboration with researchers in Cambridge and Panama as well as coordination with many different labs working on Heliconius biology, genome assembly and genome databases. Enthusiasm, determination and the capacity to work independently are also essential.

The successful applicant will be strongly encouraged to apply for fellowship funding to continue this work independently in Cambridge.

Fixed-term: The funds for this post are available for 18 months in the first instance.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PF13309 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Senior Research Laboratory Technician (Part Time, Fixed Term)

From Jobs at the University of Cambridge. Published on Sep 01, 2017.

Applications are invited for a part-time (29.2 hours per week: Monday to Friday with reduced hours or a 4-day week) BBSRC funded Research Laboratory Technician position to join the lab of Dr. Paul Conduit in the Department of Zoology, located in central Cambridge. The post-holder will be part of a vibrant team of researchers who use fruit flies to study how microtubule formation is regulated in cells.

The post-holder's primary responsibilities will be to maintain the lab's fly stock collection, help with fly handling and fly crosses, manage lab databases, organise lab meetings, process orders and help in the day-to-day running of the lab. They will also be expected to support lab members in their research and to participate in experiments as and when required. Training in fly handling and molecular biology will be provided.

The appointment will start 1st January 2018, or as soon as possible thereafter.

Essential skills: - Good interpersonal skills and an ability to work as part of a team - The ability to organise time and work effectively, independently and responsibly

Preferred skills: - Prior experience of working with Drosophila would be an advantage, but not essential - Prior experience in molecular biology would be an advantage, but not essential

Informal enquiries are welcomed and can be addressed to Dr. Paul Conduit ptc29@cam.ac.uk.

Please see the lab website for more information on our research http://conduitlab.zoo.cam.ac.uk/.

Fixed-term: The funds for this post are available for up to 36 months.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please quote reference PF13050 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.