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Oswald, M. C. W., Garnham, N., Sweeney, S. T. and Landgraf, M. (2018). Regulation of neuronal development and function by ROS. FEBS Lett. DOI: 10.1002/1873-3468.12972.

Oswald MCW, Brooks PS, Zwart MF, Mukherjee A, West RJH, Morarach K, Sweeney ST and Landgraf M. (2017). Reactive Oxygen Species Regulate Activity-Dependent Neuronal Structural Plasticity.  bioRxiv 081968.  DOI: dx.doi.org/10.1101/081968 

Ng, J., Browning, A., Lechner, L., Terada, M., Howard, G. and Jefferis, G. S. X. E. (2016). Genetically targeted 3D visualisation of Drosophila neurons under Electron Microscopy and X-Ray Microscopy using miniSOG. Sci Rep 6, 38863.  DOI:10.1038/srep38863

Zwart MF, Pulver SR, Truman JW, Fushiki A, Fetter, RD, Cardona A, Landgraf M. (2016). Selective Inhibition Mediates the Sequential Recruitment of Motor Pools. Neuron 91(3):615-628.  DOI: 10.1016/j.neuron.2016.06.031.  

Peco E, Davla S, Camp D, Stacey S, Landgraf M, van Meyel D. (2016). Drosophila astrocytes cover specific territories of CNS neuropil and are instructed to differentiate by Prospero, a key effector of Notch. Development. 143(7):1170-1181.   DOI: 10.1242/dev.133165.    

Picao-Osorio J, Johnston J, Landgraf M, Berni J, Alonso CR (2015).  MicroRNA-encoded behavior in Drosophila. Science 350: 815–820.  DOI: 10.1126/science.aad0217     

Heckscher ES, Zarin AA, Faumont S, Clark MQ, Manning L, Fushiki A, Schneider-Mizell CM, Fetter RD, Truman JW, Zwart MF, Landgraf M, Cardona A, Lockery SR, Doe CQ. Even-Skipped(+) Interneurons Are Core Components of a Sensorimotor Circuit that Maintains Left-Right Symmetric Muscle Contraction Amplitude. Neuron (September 30, 2015). doi: 10.1016/j.neuron.2015.09.009.

Berni J. Genetic dissection of a regionally differentiated network for exploratory behavior in Drosophila larvae. Curr Biol 25: 1319–1326, 2015.

Couton L, Mauss AS, Yunusov T, Diegelmann S, Evers JF, Landgraf M. Development of connectivity in a motoneuronal network in Drosophila larvae. Curr Biol 25: 568–576, 2015. DOI: 10.1016/j.cub.2014.12.056.  (see also Dispatch by Sternberg JR, Wyart C. Neuronal wiring: linking dendrite placement to synapse formation. Curr Biol 25: R190–1, 2015.)

Diao F, Ironfield H, Luan H, Diao F, Shropshire WC, Ewer J, Marr E, Potter CJ, Landgraf M, White BH. Plug-and-Play Genetic Access to Drosophila Cell Types using Exchangeable Exon Cassettes. Cell Rep 10: 1410–1421, 2015. DOI:  10.1016/j.celrep.2015.01.059

Bujdoso R, Landgraf M, Jackson WS, Thackray AM. Prion-induced neurotoxicity: Possible role for cell cycle activity and DNA damage response. World J Virol 4: 188–197, 2015.

Lu CS, Zhai B, Mauss A, Landgraf M, Gygi S, Van Vactor D. MicroRNA-8 promotes robust motor axon targeting by coordinate regulation of cell adhesion molecules during synapse development. Philos Trans R Soc Lond, B, Biol Sci 369, 2014.

Singh AP, Das RN, Rao G, Aggarwal A, Diegelmann S, Evers JF, Karandikar H, Landgraf M, Rodrigues V, VijayRaghavan K. Sensory neuron-derived eph regulates glomerular arbors and modulatory function of a central serotonergic neuron. PLoS Genet 9: e1003452, 2013.

Zwart MF, Randlett O, Evers JF, Landgraf M. Dendritic growth gated by a steroid hormone receptor underlies increases in activity in the developing Drosophila locomotor system. Proc Natl Acad Sci U S A (September 16, 2013). DOI: 10.1073/pnas.1311711110.

Berni J, Pulver SR, Griffith LC, Bate M (2012) Autonomous Circuitry for Substrate Exploration in Freely Moving Drosophila Larvae. Curr Biol 22(20): 1-10

Thackray AM, Muhammad F, Zhang C, Di Y, Jahn TR, Landgraf M, Crowther DC, Evers JF, Bujdoso R (2012) Ovine PrP transgenic Drosophila show reduced locomotor activity and decreased survival. Biochem J 444: 487-495

Crisp S, Evers JF, Bate M (2011) Endogenous patterns of activity are required for the maturation of a motor network. J Neurosci 31(29):10445-50

Berni J, Muldal AM, Pulver SR (2010) Using Neurogenetics and the Warmth-Gated Ion Channel TRPA1 to Study the Neural Basis of Behavior in Drosophila. The Journal of Undergraduate Neuroscience Education 9(1):A5-A14

Nicolai L, Ramaekers A, Raemaekers T, Drozdzecki A, Mauss A, Yan J, Landgraf M, Annaert W, Hassan B (2010) A genetically encoded dendritic marker sheds light on neuronal connectivity in Drosophila. PNAS 107(47):20553-8

Nair A, Bate M, Pulver SR (2010) Characterization of voltage-gated ionic currents in a peripheral sensory neuron in larval Drosophila. BMC Res Notes 2;3:154.

Mauss A, Tripodi M, Evers JF, Landgraf M (2009) Midline signalling systems direct the formation of a neural map by dendritic targeting in the Drosophila motor system. PLoS Biol 7(9):e1000200.

Zlatic M, Li F, Strigini M, Grueber W, Bate M (2009) Positional cues in the Drosophila nerve cord: semaphorins pattern the dorso-ventral axis. PLoS Biol 7(6):e1000135.

Tripodi M, Evers JF, Mauss A, Bate M, Landgraf M (2008) Structural homeostasis: compensatory adjustments of dendritic arbor geometry in response to variations of synaptic input. PLoS Biol 6(10):e260.

Crisp S, Evers JF, Fiala A, Bate M (2008) The development of motor coordination in Drosophila embryos. Development 135(22):3707-17.

Diegelmann S, Bate M, Landgraf M (2008) Gateway cloning vectors for the LexA-based binary expression system in Drosophila. Fly 2(4):236-9.

Ou Y, Chwalla B, Landgraf M, van Meyel DJ (2008) Identification of genes influencing dendrite morphogenesis in developing peripheral sensory and central motor neurons. Neural Dev 10;3:16.

Dixit R, Vijayraghavan K, Bate M (2008) Hox genes and the regulation of movement in Drosophila. Dev Neurobiol 68(3):309-16.

Roy B, Singh AP, Shetty C, Chaudhary V, North A, Landgraf M, Vijayraghavan K, Rodrigues V (2007) Metamorphosis of an identified serotonergic neuron in the Drosophila olfactory system. Neural Dev 24;2:20.

Landgraf M, Thor S (2006) Development and structure of motoneurons. Int Rev Neurobiol 75:33-53.

Strigini M, Cantera R, Morin X, Bastiani MJ, Bate M, Karagogeos D (2006) The IgLON protein Lachesin is required for the blood-brain barrier in Drosophila. Mol Cell Neurosci 32(1-2):91-101.

Landgraf M, Thor S (2006) Development of Drosophila motoneurons: specification and morphology. Semin Cell Dev Biol 17(1):3-11.

Collaborators

Richard Baines (Faculty of Life Sciences, University of Manchester)

Jimena Berni (University of Sussex)

Albert Cardona (Department of Physiology, Development and Neuroscience, University of Cambridge)

Jan Felix Evers (Centre for Organismal Studies Heidelberg, Ruprecht-Karls-Universität, Heidelberg)

Gregory Jefferis (MRC-LMB, Cambridge; Department of Zoology, University of Cambridge)

Timothy O’Leary (Department of Engineering, University of Cambridge)

Tony Southall (Imperial College London)

Sean Sweeney (Department of Zoology, University of York)

Jelle van den Ameele (MRC Mitochondrial Biology Unit, Cambridge)

Marta Zlatic (Department of Zoology, University of Cambridge)

Positions

If you are interested in joining our group, please e-mail Matthias Landgraf to discuss research projects and positions/lab space. We have been successful in obtaining support for promising scientists and are happy to help.