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Department of Zoology


Drechsler M, Giavazzi F, Cerbino R, Palacios IM. Active diffusion and advection in Drosophila oocytes result from the interplay of actin and microtubules.  Nature Communications. 8, 1520 (2017).  doi:10.1038/s41467-017-01414-6

Bermudo MDM, Gebel L, Palacios IM (2017) DrosAfrica: Building an African biomedical research community using Drosophila. Seminars in Cell & Developmental Biology. doi: 10.1016/j.semcdb.2017.08.044

Ng BF, Selvaraj GK, Santa-Cruz Mateos C, Grosheva I, Alvarez-Garcia I, Martín-Bermudo MD and Palacios IM (2016) Alpha-Spectrin and Integrins act together to regulate actomyosin and columnarization, and to maintain a monolayered follicular epithelium.Development.2016 Apr 15;143(8):1388-99.

Saavedra P, Brittle A, Palacios IM, Strutt D, Casal J and Lawrence PA (2016). Planar cell polarity: the Dachsous-Fat system contributes differently to the embryonic and larval stages of Drosophila.Biology open.2016;5(4):397-408.

Palacios IM (2014). Hop on hop off: polysomes take a tour of the cell on endosomes.J. Cell Biology.2014 Feb 3;204(3):287-9.

Gómez-Lamarca MJ, Cobreros-Reguera L, Ibáñez-Jiménez B,Palacios IM and Martín-Bermudo MD. (2014). Integrins regulate epithelial cell differentiation by modulating Notch activity.J. Cell Science.2014 Nov 1;127(21):4667-78.

Saavedra P, Vincent JP, Palacios IM, Lawrence PA, Casal J. Plasticity of both planar cell polarity and cell identity during the development of Drosophila. Elife. 2014 Feb 11;3:e01569. doi: 10.7554/eLife.01569.

Palacios IM. Hop-on hop-off: Polysomes take a tour of the cell on endosomes. J Cell Biol. 2014 Feb 3;204(3):287-9. doi: 10.1083/jcb.201401019.

Williams LS, Ganguly S, Loiseau P, Ng BF, and Palacios IM. The auto-inhibitory domain and the ATP-independent microtubule-binding region of Kinesin Heavy Chain are major functional domains for transport in the Drosophila germline. Development. 2014 Jan;141(1):176-86. doi: 10.1242/dev.097592. Epub 2013 Nov 20.

Palacios IM. Nonsense mediated RNA Decay (2012). Briefings in Functional Genomics. Nov 11 (Epub ahead of print).

Ganguly S*, Williams LS*, Palacios IM**, and Goldstein RE** (2012) “Cytoplasmic streaming in Drosophila oocytes varies with kinesin activity and correlates with the microtubule cytoskeleton architecture”. PNAS.18;109(38):15109-14.

* Contributed equally as first authors.
** Contributed equally as senior and corresponding authors

Avery P, Vicente-Crespo M, Francis D, Nashchekina O, Alonso CR, and Palacios IM (2011) “Drosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent manner”. RNA 17: 624-638.

Described as “of outstanding interest” by Hwang, J and Maquat, LE, Curr. Opin. Genet Dev. 2011; 21(4):422-30.

Vicente-Crespo M and Palacios IM (2010) “Nonsense-mediated mRNA decay and Development:shoot the messenger to survive?” Biochemical Society Transactions Dec;38(6):1500-5.

Loiseau P, Davies T, Williams LS, Mishima M, and Palacios IM. (2010) “Drosophila Pat1 is required for Kinesin-1 to transport cargo and to maximize its motility”. Development 137, 2763-2772

Meignin C, Alvarez-Garcia I, Davis I, Palacios IM. (2007). "The salvador-warts-hippo pathway is required for epithelial proliferation and axis specification in Drosophila". Current Biology. Nov; 17(21):1871-8.

Dispatch in Current Biology 17, Issue 23 (2007)

Palacios IM. (2007). "How does an mRNA find its way? Intracellular localisation of transcripts". Seminars in Cell and Developmental Biology. Apr;18(2):163-170.

Palacios IM, Gatfield D, St Johnston D and Izaurralde E (2004). An eIF4AIII-containing complex required for mRNA localisation and nonsense-mediated mRNA decay. Nature 427:753-757.

News and Views, Nature Cell Biology 6, 285 - 287 (2004)

Macchi P., Kroening S., Palacios IM., Baldassa S., Grunewald B., Ambrosino C., Lupas A., St Johnston D. and Kiebler M. (2003). Barentsz, a new component of the Staufen-containing ribonucleoprotein particles in mammalian cells, interacts with Staufen in a RNA-dependent manner. Journal of Neuroscience 23(13):5778-5788.

Palacios IM. (2002). RNA Processing: Splicing and the cytoplasmic localisation of mRNA. Current Biology 12:50-52.

Palacios IM. and St Johnston D. (2002). Kinesin light chain-independent function of the Kinesin heavy chain in cytoplasmic streaming, and posterior localisation in the Drosophila oocyte. Development 129(23):5473-5485.

Benton, R, Palacios IM. and St Johnston D. (2002). Drosophila 14-3-3/PAR-5 is an essential mediator of PAR-1 function in axis formation. Developmental Cell 3(5):659-671.

Palacios, IM. and St Johnston D. (2001). Getting the Message Across: The Intracellular Localization of mRNAs in Higher Eukaryotes. Annual Review of Cell and Developmental Biology 17:569-614.

van Eeden, FJM., Palacios IM., Petronczki M., Weston M., and St Johnston D. (2001). Barentsz is essential for the posterior localization of oskar mRNA and co-localizes with it to the posterior pole. Journal of Cell Biology 154:511-523.

Wagner C., Palacios I., Jaeger L., St Johnston D., Ehresmann B., Ehresmann C., and Brunel C. (2001). Dimerization of the 3'UTR of bicoid mRNA Involves a Two-step Mechanism. Journal of Molecular Biology 313(3):511-524.

Palacios, I. and Izaurralde, E. (2000). RNA transport and localisation. Encyclopedia Life Sciences, (Nature & MacMillan Publishers) (

Dingwall, C. and Palacios, I. (1997). in vitro systems for the reconstitution of UsnRNP and protein nuclear import. Methods in Cell Biology 53:517-543.

Palacios, I., Hetzer, M., Adam, S.A. and Mattaj, I.W. (1997). Nuclear import of U snRNPs requires importin β. The EMBO Journal 16: 6783-6792.

Perales, B., De La Luna, S., Palacios, I., and Ortin, J. (1996). Mutational analysis identifies functional domains in the Influenza A virus PB2 polymerase subunit. Journal of Virology 70: 1678-1686.

Palacios, I., Weis, K., Klebe, C., Mattaj, I.W., and Dingwall, C. (1996). RAN/TC4 mutants identify a common requirement for U snRNP and protein import into the nucleus. Journal of Cell Biology 133: 485-494.

Palacios, I. and Izaurralde, E. (1996). Nucleocytoplasmic transport over the Garda Lake. Trends in Cell Biology 7:81-83.

Boelens, W.C., Palacios, I., and Mattaj, I.W. (1995). Nuclear retention of RNA as a mechanism for localization. RNA 1:273-283.