Biography
I am the Project Team Leader for the Drosophila Connectomics group, started in October 2016. The project aims to build the adult olfactory connectome of Drosophila, that is, to describe the neurons involved in innate and learned olfactory behaviour, and its connections to other neurons. We are part of a consortium of groups in Cambridge (Jefferis, Landgraf), Oxford (Waddell) and Janelia Research Campus (Rubin, Bock) that are doing this, using a whole brain EM volume generated at Janelia by Davi Bock's group (Zheng et al., 2017). For more detail on our research, see our group page.
I have also been a part of the Virtual Fly Brain project - the neuroinformatic hub for Drosophila neuroscience information - since 2011, working on data curation and image analysis, and now as a Co-Investigator.
Publications
P Schlegel (1), M Costa (1), GSXE Jefferis (2017) Learning from Connectomics on the fly, Current Opinion in Insect Science, 24:96–105
E Marin & M Costa (2017) Sensory Neurobiology: Wet Fly Fishing, Current Biology, 27:R833–R852
Costa, M., A.D., Manton, Ostrovsky, J.D., Prohaska, S. and Jefferis, G.S.X.E. (2016).NBLAST: Rapid, sensitive comparison of neuronal structure and construction of neuron family databases. Neuron, 91(2), 293-311
Manton, J.D., Ostrovsky, A.D., Goetz, L., Costa, M., Rohlfing, T., and Jefferis, G.S.X.E. (2014).Combining genome-scale Drosophila 3D neuroanatomical data by bridging template brains. biorxiv
Costa, M., Calleja, M., Alonso, C. R. and Simpson, P. (2013). The bristle patterning genes hairy and extramacrochaetae regulate the development of structures required for flight in Diptera.Dev. Biol. 1–11.
Costa M., Reeve S., Grumbling G., Osumi-Sutherland D. (2013). The Drosophila anatomy ontology. Journal of Biomedical Semantics 4 (32).
- R. C. Court, J. D. Armstrong, J. Borner, G. Card, M. Costa, M. Dickinson, C. Duch, W. Korff, R. Mann, D. Merritt, R. Murphey, et al. (2017). A Systematic Nomenclature for the Drosophila Ventral Nervous System. bioRxiv, 122952.
- S. J. Marygold, G. Antonazzo, H. Attrill, M. Costa, M. A. Crosby, G. dos Santos, J. L. Goodman, L. S. Gramates, B. B. Matthews, A. J. Rey, et al. (2016). Exploring FlyBase Data Using QuickSearch. Current Protocols in Bioinformatics, 1–31.
- Costa, M., A.D., Manton, Ostrovsky, J.D., Prohaska, S. and Jefferis, G.S.X.E. (2014).NBLAST: Rapid, sensitive comparison of neuronal structure and construction of neuron family databases. biorxiv
- Araya, C., Tawk, M., Girdler, G. C., Costa, M., Carmona-Fontaine, C. and Clarke, J. D. (2014).Mesoderm is required for coordinated cell movements within zebrafish neural plate in vivo. Neural Dev. 9, 9.
- Correia, C. (1), Costa, M. (1), Moraes, F. (1), Bom J., Nóvoa A. and Mallo, M. (2007). Bmp2 is required for migration but not for induction of neural crest cells in the mouse. Developmental Dynamics 236, 2493-2501. (1) equal contributors.
